Výsledky vyhledávání - 9085362 OR The role of mitochondria in aging
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1Hlavní autor Jang, Ji Yong, Blum, Arnon, Liu, Jie, Finkel, Toren“… Increasing evidence, however, points to a role for alterations in mitochondrial function as a potential central regulator of the aging process…”
Publikováno v The Journal of clinical investigation (01. 09. 2018)
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2Hlavní autor Bratic, Ana, Larsson, Nils-Göran“…Over the last decade, accumulating evidence has suggested a causative link between mitochondrial dysfunction and major phenotypes associated with aging…”
Publikováno v The Journal of clinical investigation (01. 03. 2013)
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3Hlavní autor Gonzalez-Freire, Marta, de Cabo, Rafael, Bernier, Michel, Sollott, Steven J, Fabbri, Elisa, Navas, Placido, Ferrucci, Luigi“… The purpose of this review is to scan the ever-growing literature on mitochondria from the perspective of aging research and try to identify…”
Publikováno v The journals of gerontology. Series A, Biological sciences and medical sciences (01. 11. 2015)
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5“… As the mitochondrion is an important source of reactive oxygen species (ROS), this organelle is regarded as a key intracellular player in this process and a large amount of data supports the role of mitochondrial ROS production during aging…”
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6Hlavní autor May-Panloup, Pascale, Boucret, Lisa, Chao de la Barca, Juan-Manuel, Desquiret-Dumas, Valérie, Ferré-L'Hotellier, Véronique, Morinière, Catherine, Descamps, Philippe, Procaccio, Vincent, Reynier, Pascal“… Mitochondria play a central role in follicular atresia and could be the main target of the ooplasmic factors determining oocyte quality adversely affected by ageing…”
Publikováno v Human reproduction update (01. 11. 2016)
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7“… During aging, damaged mitochondria that produce less ATP and more reactive oxygen species (ROS) accumulate. The current consensus is that ROS cause oxidative stress…”
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8Hlavní autor Nilsson, Mats I, Tarnopolsky, Mark A“…Mitochondria orchestrate the life and death of most eukaryotic cells by virtue of their ability to supply adenosine triphosphate from aerobic respiration for growth, development, and maintenance…”
Publikováno v Biology (Basel, Switzerland) (11. 05. 2019)
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10Hlavní autor Zhu, Yukun, Liu, Xuewen, Ding, Xuelu, Wang, Fei, Geng, Xin“… Telomeres, the repetitive DNA repeat sequences at the end of linear eukaryotic chromosomes protecting chromosome ends from degradation and illegitimate recombination, play a crucial role in cell fate and aging…”
Publikováno v Biogerontology (Dordrecht) (01. 02. 2019)
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11Hlavní autor Kauppila, Timo E.S., Kauppila, Johanna H.K., Larsson, Nils-Göran“…Mitochondria were first postulated to contribute to aging more than 40 years ago…”
Publikováno v Cell metabolism (10. 01. 2017)
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12Hlavní autor Melhuish Beaupre, Lindsay M., Brown, Gregory M., Gonçalves, Vanessa F., Kennedy, James L.“… More recently, evidence indicates that it also plays an important role in neuroprotection. The beginning of our review will summarize this literature…”
Publikováno v Translational psychiatry (02. 06. 2021)
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13Hlavní autor NIEMANN, Bernd, YING CHEN, TESCHNER, Mirja, LING LI, SILBER, Rolf-Edgar, ROHRBACH, Susanne“…Objectives The purpose of the present study was to investigate the influence of obesity on cardiac aging…”
Publikováno v Journal of the American College of Cardiology (01. 02. 2011)
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14Hlavní autor Sreedhar, Annapoorna, Aguilera-Aguirre, Leopoldo, Singh, Keshav K.“…) that is located on the inner membrane of the mitochondria. However, reactive oxygen species (ROS) like superoxide, singlet oxygen, peroxides are inevitably produced…”
Publikováno v Cell death & disease (09. 06. 2020)
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15Hlavní autor Green, Douglas R., Galluzzi, Lorenzo, Kroemer, Guido“… Moreover, mitochondria have an important role in pro-inflammatory signaling. Autophagic turnover of cellular constituents, be it general or specific for mitochondria (mitophagy…”
Publikováno v Science (American Association for the Advancement of Science) (26. 08. 2011)
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17Hlavní autor Li, Yu-juan, Jin, Xiao, Li, Dan, Lu, Jing, Zhang, Xiao-nan, Yang, Sheng-jie, Zhao, Yi-xi, Wu, Min“… Mitochondria play an important role in vascular aging. In endothelial and smooth muscle cells, multiple changes in the mitochondrial structure and function contribute…”
Publikováno v Biomedicine & pharmacotherapy (01. 12. 2022)
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18Hlavní autor Moltedo, Ornella, Remondelli, Paolo, Amodio, Giuseppina“…), may play a crucial role in aging and in the development of age-associated diseases. As emerged in the last decade, MERCs behave as signaling hubs composed by structural…”
Publikováno v Frontiers in cell and developmental biology (21. 08. 2019)
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19Hlavní autor Chiang, Jasmine L., Shukla, Pallavi, Pagidas, Kelly, Ahmed, Noha S., Karri, Srinivasu, Gunn, Deidre D., Hurd, William W., Singh, Keshav K.“…•Mitochondrial dysfunction drives ovarian aging.•Rejuvenating mitochondria with nutrient therapy may improve fertility…”
Publikováno v Ageing research reviews (01. 11. 2020)
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20Hlavní autor Swerdlow, Russell H.“… appears to play a role in both AD and brain aging. Specific issues addressed include the question of whether AD and brain aging should be conceptually lumped or split…”
Publikováno v Biochimica et biophysica acta. Molecular basis of disease (01. 12. 2011)
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